Amyloid Clumps, a Key Feature of Alzheimer’s Disease, Found in Young Adult Brains

Amyloid Clumps, a Key Feature of Alzheimer’s Disease, Found in Young Adult Brains
shutterstock_111506315Researchers at Northwestern University have recently reported in the journal Brain that the amyloid plaques characteristic of Alzheimer’s disease can be found in young adult brains. The study is entitled “Neuronal amyloid-β accumulation within cholinergic basal forebrain in aging and Alzheimer’s disease.” Alzheimer’s disease is an age-related, neurodegenerative disorder characterized by cognitive and behavioral problems. Individuals with the disease initially experience memory loss and confusion that gradually leads to behavior and personality changes, a decline in cognitive abilities, and ultimately to severe loss of mental function. Alzheimer’s disease is characterized by brain formation of amyloid plaques (composed of beta-amyloid proteins, remnants of neurons and other nerve cells and proteins), and the loss of the connection between neurons that are responsible for memory and learning leading to their eventual death. As neurons die, the affected regions of the brain begin to shrink. It is well-known that in Alzheimer’s, amyloid proteins accumulate, forming amyloid plaques outside ne
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