Researchers Develop Complete Human Brain Model In The Lab To Study Alzheimer’s Disease

Researchers Develop Complete Human Brain Model In The Lab To Study Alzheimer’s Disease
This week, Ohio State University (OSU) researcher, Dr. ​Rene Anand, PhD, MS whose laboratory is focused on studying how genes and the environment interact to increase susceptibility to neurodevelopmental, neuropsychiatric and neurodegenerative disorders in an effort to develop brain organoids (three-dimensional organ-bud grown in a laboratory) to study autism, drug addiction and Parkinson's disease, revealed his team developed a nearly complete human brain that equals the brain maturity of a 5-week-old fetus. The presentation took place during the 2015 Military Health System Research Symposium in Ft. Lauderdale, Florida on Tuesday August 18, and highlighted the laboratory grown organ’s functioning neurons, as well as normal chemical signalling activity, using high-resolution imaging technology. In a University press release , Dr. Anand, stated, “It not only looks like the developing brain, its diverse cell types express nearly all genes like a brain. We’ve struggled for a long time trying to solve complex brain disease problems that cause tremendous pain and suffering. The power of this brain model bodes very well for human health because it gives us better and more relevant options to test and develop therapeutics other than rodents.” Dr. Anand, added “In central nervous system diseases, this will enable studies of either
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