Researchers Identify Final Step Killing Damaged Neurons in Self-destructive Process

Researchers Identify Final Step Killing Damaged Neurons in Self-destructive Process
Researchers have identified the factor at the end of a molecular chain of events killing nerve cells which have been exposed to damage from disease processes such as stroke and possibly Alzheimer's or a wide variety of other injuries. The study, “A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1,” published in the journal Science, may pave the way for the development of treatments able to slow or stop the process, saving neurons from death. The findings built on the previous work of two research groups at Johns Hopkins Universit
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