Posts by: Jonathan Grinstein

News

A study has identified the gene that explains why excitatory neurons — brain cells that excite their targets — are more vulnerable to accumulations of abnormal tau protein aggregates, ... Read more

December 14, 2018December 14, 2018

Saliva-Based Test Proposed to Diagnose Alzheimer’s, Mild Cognitive Impairment

News

A new test using patients’ saliva may be helpful in distinguishing between Alzheimer’s, mild cognitive impairment, and normal brain function, new research reports. The study, “Alzheimer’s Biomarkers From Multiple Modalities Selectively ... Read more

December 12, 2018December 12, 2018

Molecule That Binds to Tau and Works as Tracer Might Help to Diagnose and Treat Alzheimer’s, Study Reports

News

A newly identified “tracer” molecule that binds to and “lights up” aggregates of tau — a protein linked to Alzheimer’s disease and related dementias – showed promise as a way to ... Read more

November 30, 2018November 30, 2018

Alzheimer’s Patient is First to Get Focused Ultrasound Treatment

News

A new treatment using focused ultrasound to treat early-stage Alzheimer’s disease was successfully administered to a patient. The treatment, which involves incisionless surgery and no pharmaceuticals, is part of a worldwide Phase 2 ... Read more

November 28, 2018November 28, 2018

DNA Vaccine Safely Lowers Toxic Amyloid and Tau Aggregates in Brains of Mice with Alzheimer’s, Study Says

News

Use of an active DNA vaccine in mice with hallmarks of Alzheimer’s disease significantly lowered the toxic accumulation of amyloid plaques and tau without triggering severe brain swelling — a damaging complication ... Read more

November 21, 2018November 21, 2018

Improved Brain Immunotherapy Delivery Strategy Uses Brain’s Natural Plumbing System, Study Reports

News

A new approach for delivering antibody-based therapeutics to the brain by exploiting the fluid surrounding the brain’s blood vessels was proposed in a recent preclinical study. This improved brain immunotherapy ... Read more