A critical but vulnerable brain region seems to be the first area disturbed by late onset Alzheimer’s disease, and to be a region more essential for preserving cognitive function in later life than previously thought, according to a review, “The Locus Coeruleus: Essential for Maintaining Cognitive…
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Researchers at the Johns Hopkins Bloomberg School of Public Health have developed “mini-brains” that may present a more accurate and effective way of testing new drugs for many neurological disorders, such as Alzheimer’s disease. These human cell-derived structures, which represent an existing new alternative to animal testing, were recently discussed in a…
Scientists have discovered the anti-cancer drug bexarotene may target the first step in the toxic chain activity that leads to the death of brain cells, paving the way to new Alzheimer’s therapies. The study, conducted by an international team of researchers from the University of Cambridge in England, Lund University in…
Researchers have discovered that the skeleton surrounding the nucleus of brain cells is dysfunctional in Alzheimer’s disease patients, which could lead to neuronal death. The study, “Lamin Dysfunction Mediates Neurodegeneration in Tauopathies,” was published in Current Biology. The lamin nucleoskeleton that surrounds the nucleus of cells is important in the…
As part of Allianz Championship week in Boca Raton, Florida, Allianz encouraged golf enthusiasts to share their favorite golf memories on Facebook, Twitter, Instagram and other social media sites — using the hashtag #AllianzBirdies — to raise awareness of the Alzheimer’s Association and its work. Two company groups — Allianz Life and Allianz Global…
Researchers at Harvard Medical School and the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology have developed a system that allows them to study individual human neurons and other nervous system cells. Researchers have identified the subpopulations of cells responsible for the secretion of Alzheimer’s disease-relevant factors…
Tel Aviv University and Harvard researchers have found a new biomarker for cognitive aging and Alzheimer’s disease (AD). Diagnosing Alzheimer’s is not an easy task. The process employs measurements of memory impairment, cognitive skills, functional abilities, and behavioral changes, as well as brain imaging and analyses of the cerebrospinal fluid.
While there is abundant evidence that seafood consumption protects from the development of dementia, little is known about the effects of mercury — a heavy metal present in seafood — on the risk of Alzheimer’s disease. A new study shows that seafood mercury does not at all alter disease risk in older adults.
According to a new study from Imperial College London, England, long-term survivors of traumatic brain injury who develop brain issues have an increased number of amyloid-β (Aβ) plaques, a hallmark of Alzheimer’s disease. The research paper, “Amyloid pathology and axonal injury after brain trauma,” was recently published online in…
A study from Tel Aviv University found that the IGF-1 receptor, associated with an increased lifespan in mice, is mediating hyperactivity in the hippocampus of the brain. Hippocampal hyperactivity is linked to conditions that increase the risk for Alzheimer’s disease (AD), and the findings may pave the way for new AD treatments…
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