A research article, titled, “Subtle Cognitive Decline and Biomarker Staging in Preclinical Alzheimer’s Disease” recently published in the Journal of Alzheimer’s Disease by a team of investigators from the University of California in San Diego (UCSD) School of Medicine and Veterans Affairs San Diego…
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A study recently published in the journal Neuropsychopharmacology revealed that the inhibition of a gene called phosphodiesterase-4B (PDE4B) in mice enhances the animals’ cognitive abilities. The work was conducted by an international team of researchers and is entitled “Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis…
The biggest risk factor for Alzheimer’s disease (AD) is aging. After the age of 65 the risk doubles every 5 years, with over 40% of those aged 85 and older expected to develop the debilitating condition. Scientists at the Washington University School of Medicine in St. Louis managed to identify some of the crucial changes that occur in the brain…
A scientist from the University of Oklahoma is developing a new therapy to address Alzheimer’s disease using “biopharmaceutical proteases” to destroy the toxic plaque that piles up in the brain of Alzheimer’s patients. This approach will have significantly lower costs in the treatment of the disease while at the same time it has the potential to…
In a recent study published in the journal Alzheimer’s & Dementia a team of researchers found that eating a group of certain foods known as the MIND diet may slow cognitive decline among aging adults, even when the person is not at risk of developing Alzheimer’s…
Soon-to-be former partners in a promising Alzheimer’s research program, Eli Lilly and Co. and the University of California San Diego (UCSD) have moved a step closer to ending the contract that covers the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s disease (A4) study, a groundbreaking clinical trial that aims to test solanezumab. This Phase…
In a recent study published in the International Journal of Geriatric Psychiatry, a team of researchers from the ECU’s Centre of Excellence for Alzheimer’s Research and Care at Edith Cowan University have found a strong association between depressive symptoms and cognitive decline. In the study titled “…
A study recently published in the Journal of Alzheimer’s Disease revealed that intranasal administration of insulin can be a potential therapeutic strategy for Alzheimer’s disease and dementia conditions. The study entitled “Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on…
In a recent study published in Angewandte Chemie, a team of researchers from the University of Melbourne have identified that a specific protein known for its involvement in the progression of Alzheimer’s disease (AD) has properties that could be beneficial for human health. The study findings may help…
Alzheimer’s disease is a neurodegenerative disorder characterized by cognitive and behavioral problems. It is the most common form of dementia in the elderly with patients initially experiencing memory loss and confusion that gradually leads to behavior and personality changes, a decline in cognitive abilities and ultimately to severe loss of…
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