News

In a new study entitled “Metabotropic P2Y1 receptor signaling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model” published in Nature Communications, Andrea Delekate and colleagues examined the astrocytic network underlying pathways that may be implicated in Alzheimer’s disease (AD), and provide solid evidence for…

Biopharmaceutical company Anavex Life Sciences Corp. recently presented encouraging results from their phase 1 clinical trial, a study testing the company’s lead investigational oral treatment for Alzheimer’s disease, Anavex 2-73, at CNS Summit 2014 in Boca Raton, Florida. After assessing the drug’s safety and effectiveness, the medication…

A recent review from Schichun Tu and colleagues entitled “Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease” was published this week in the journal Molecular Neurodegeneration. The aim of the study was to discuss the state of current evidence suggesting that the synaptic loss found in…

Cognition Therapeutics Inc. announced the discovery of a new drug target in the brain that plays a role in the development of Alzheimer’s disease, and their investigation of new drug candidates to reverse the memory loss associated with Alzheimer’s. The two studies were entitled “Alzheimer’s therapeutics targeting Amyloid beta 1-42…

The Alzheimer’s Foundation of America (AFA) is organizing a public awareness campaign to remember the importance of keeping memories alive. As part of the campaign, they are asking people to share beloved memories by posting old photos on their social networks using the hashtag #RememberTogether. The Remember Together campaign is one of…

In a recent study entitled “Pharmacological chaperones stabilize retorter to limit APP processing,” the authors report that pharmacologic chaperones have a highly positive impact on a multiprotein complex — the retromer — that has been linked to Alzheimer’s disease. The study was published in the April issue…

In patients suffering from Alzheimer’s disease or dealing with the aftermath of a stroke, a lack of orientation — as if their inner perception of the world in which they always lived in just disappeared — is common. Researchers from the University of California, San Diego School of Medicine induced…

In a research article entitled “Primary age-related tauopathy (PART): a common pathology associated with human aging,” recently published in the Acta Neuropathologica, researchers uncovered new insights into an Alzheimers-related memory disorder. This multi-institutional study, co-led by…

In neurodegenerative disorders such as Alzheimer’s Disease, the loss of memory is often a defining symptom. In a study entitled “FASTKD2 is associated with memory and hippocampal structure in older adults” the authors report to have found a new genetic variant in the FASTKD2 gene that is associated with…

In a recent study entitled “Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion” the authors developed a new imaging protocol that allows detection and examination of Alzheimer’s Disease typical beta-amyloid plaques. The study was published in the online issue of…