This short video from DNews focuses on an innovative study where gene therapy was used to reduce the amount of amyloid plaques in mouse models.
Alzheimer’s disease is the sixth leading cause of death in America and affects more than five million people. Proteins called Amyloid-beta peptides are responsible for forming deposits of plaque in the brain, which kill brain cells. A study found that the gene PGC1-A interferes with the production of these peptides, which resulted in fewer plaques in the mice when injected with a modified virus of PGC1-A. Researchers are hoping this will be a breakthrough in the fight against the disease.
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