Nearly half of Alzheimer’s disease patients treated with TrueBinding’s investigational therapy TB006 for at least three months showed signs of disease reversal or cognitive improvement, according to data from an open-label extension (OLE) study. The findings expand on data from a completed Phase 2a trial (NCT05074498) that…

Alzheimer’s disease is not often seen among those younger than 65, but the Youth Movement Against Alzheimer’s is getting young people involved with the neurological disorder through volunteer work, education, and advocacy. While they aren’t typically affected themselves,…

The number of people with dementia in 37 countries in and near Europe is likely to double to 18.8 million by 2050, according to Alzheimer Europe. That’s more than the 18 million predicted in previous forecasts. The Luxembourg-based organization also lowered estimates of the current dementia count by a…

Researchers at Maastricht University Medical Center in the Netherlands have developed two online apps to improve the lives of people who care for dementia patients, and will soon create one for patients themselves. One app provides caregivers with information they can use to achieve balance in their lives. Those participating in…

The writing style of a woman’s diary entries over 31 years has given researchers a glimpse into the progression of her cognitive decline from Alzheimer’s disease, revealing a relationship between language use and the transition from healthy to severe dementia. University of Toronto (UT) researchers specializing in language…

Herpes simplex virus type 1 (HSV1) may be linked to Alzheimer’s development, and antiviral therapies lower the risk of senile dementia in patients with severe herpes infections, according to a review study. The research, “Corroboration of a Major Role for Herpes Simplex Virus Type 1 in Alzheimer’s Disease,”…

Researchers have discovered a new mechanism targeted by the leukemia therapy Sprycel that may contribute to Alzheimer’s and traumatic brain injury. The team, which effectively targeted this mechanism in a mouse model of Alzheimer’s, now hopes to replicate the test in humans. The study, “Oxidation of…

The percentage of U.S. residents with Alzheimer’s disease and related dementias will double by 2060, according to the Centers for Disease Control and Prevention (CDC).  In 2014, roughly five million adults ages 65 and over had Alzheimer’s disease and related dementias (ADRD). That’s 1.6 percent of the U.S.

Intensive efforts to lower blood pressure — dropping systolic blood pressure, particularly, to lower-than-recommended levels — can reduce a person’s risk of the mild cognitive impairment that may precede Alzheimer’s and of dementia, results of clinical trial show. “This is the first randomized clinical trial to demonstrate a reduction in…

The U.S. Food and Drug Administration (FDA) approved Tonix Pharmaceuticals’ investigational new drug (IND) application to support the start of a Phase 2 trial of TNX-102 SL in Alzheimer’s patients with agitation. In December 2016, the treatment candidate was granted breakthrough therapy status — a process designated…