cognitive decline

October 31, 2018October 31, 2018

Anavex 2-73 Slows Cognitive Decline in Alzheimer’s Patients, Phase 2 Extension Trial Shows

News

Treatment with Anavex‘s investigational therapy Anavex 2-73 significantly reduces cognitive decline in people with Alzheimer’s disease and sustains their ability to perform daily activities, according to interim data from a ... Read more

August 8, 2018

Bryostatin-1 Can Reverse Cognitive Decline in Moderate-to-Severe Alzheimer’s, New Data Shows

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Neurotrope’s investigational compound Bryostatin-1 showed evidence of sustained improvement in cognition compared to placebo in patients with moderate-to-severe Alzheimer’s disease, according to additional results from a Phase 2 clinical ... Read more

July 27, 2018July 27, 2018

Latest Trial Data Shows Potential of BAN2401 in Preventing Cognitive Decline in Early Alzheimer’s

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The latest data from a Phase 2 trial (study 201) demonstrates that BAN2401 can slow cognitive decline, providing additional evidence of its potential as a disease-modifying therapy for Alzheimer’s disease, ... Read more

May 23, 2018May 23, 2018

Janssen Halts Clinical Development of Alzheimer’s Candidate Atabecestat Due to Liver Issues

News

Janssen pulled the plug on a Phase 2b/3 trial and a Phase 2 safety study of its Alzheimer’s disease experimental therapy atabecestat due to toxicity issues as a result of ... Read more

July 12, 2017

Strawberry Compound Fisetin Slows Cognitive Decline of Aging in Mouse Study

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Researchers fed the antioxidant fisetin, found in strawberries and other fruits and vegetables, to mice for seven months and found that the compound partially protected the animals from age-associated cognitive ... Read more

April 10, 2017April 10, 2017

In Senate Testimony, AFA Urges More Federal Funding for Alzheimer’s Research

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The Alzheimer’s Foundation of America (AFA), which represents more than 2,600 member organizations nationwide, testified March 29 at a Senate hearing in Washington that discussed issues related to cognitive decline. The ... Read more

April 5, 2017April 5, 2017

Study on Slower Brain Volume Loss in SuperAgers May Shed Light on Alzheimer’s, Other Dementias

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So-called “SuperAgers” lose brain volume more slowly than their normally aging peers, protecting them from dementia, according to a new study that proves yet again that Alzheimer’s disease — like other dementias ... Read more

February 8, 2017

Alzheimer’s Onset and Progression May Be Linked to Subclinical Epileptic Activity

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Epileptic activity appear to be more frequent in patients with Alzheimer’s disease than in healthy individuals and may be linked to disease progression, according to a recent study. These findings, ... Read more

February 1, 2017February 1, 2017

As Glucose Levels Fall in the Brain, Series of Molecular Reactions Seen to Kill Neurons

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Low glucose levels in the brain are known to lead memory problems and cognitive decline, and new research suggests they do so by triggering a series of molecular reactions that ultimately kill neurons. ... Read more

November 22, 2016December 6, 2016

Anavex’s Experimental Alzheimer’s Treatment Prevents Mental-acuity Decline in Clinical Trial

News

Anavex Life Sciences reported that its experimental drug Anavex 2-73 prevented further decline in mental capacity in a small Phase 2a trial involving 32 patients with mild to moderate Alzheimer’s disease. Although ... Read more

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