Roche Set to Start Two Phase 3 Trials of Gantenerumab in People with Early to Mild Alzheimer’s

The safety and efficacy of Roche’s gantenerumab, a treatment candidate for Alzheimer’s, will be tested in two global Phase 3 clinical trials in patients with early to mild forms of the disease. The studies follow a long research process that defined the therapy’s optimal dose. The GRADUATE1 (NCT03444870) and GRADUATE2…

Roche, MorphoSys Plan Experimental Clinical Trials of Gantenerumab for Alzheimer’s

Roche and MorphoSys will partner on experimental Phase 3 clinical trials to study the effectiveness and safety of gantenerumab in patients with early to mild Alzheimer’s disease. Roche, a Swiss global healthcare company, will start preparing two studies soon, according to MorphoSys, a German biotechnology company that developed gantenerumab. The trials will…

SCarletRoAD Trial of Gantenerumab in Prodromal Alzheimer’s Discontinued

German biotechnology company, MorphoSys, was informed by its partner, Swiss global health-care company, Roche, about their decision to discontinue gantenerumab‘s Phase III SCarletRoAD trial for prodromal Alzheimer’s Disease patients. This decision is supported by a recommendation from the Independent Data Monitoring Committee, and by a pre-planned futility assessment. According to Roche, the trial was…