Increasing the Activity of Certain Type of Nerve Cell Restores Cognition, Mouse Study Shows

Increasing the Activity of Certain Type of Nerve Cell Restores Cognition, Mouse Study Shows
The brain works in a coordinated matter, like a tuned orchestra, scientists say. If a single instrument is out of sync, it affects the entire ensemble. In Alzheimer's disease, damage to certain nerve cells is sufficient to alter brainwave rhythms and cause a loss of cognitive function. A new mouse study shows how enhancing the activity of inhibitory interneurons — nerve cells that work like orchestra conductors — can help rescue out-of-sync brain rhythms and restore cognitive function in Alzheimer’s. The study, “Nav1.1-Overexpressing Interneuron Transplants Restore Brain Rhythms and Cognition in a Mouse Model of Alzheimer's Disease," was published in the journal
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