Posts by: Patricia Inacio, PhD

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While caregiving for people with Alzheimer’s and other disorders has a significant detrimental impact on caregivers’ immune system, the association is weak — less than 1% — and may ... Read more

April 10, 2019April 15, 2019

Phase 1 Trial of Alzheimer’s Candidate SM07883 Doses First Participant

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A Phase 1 trial evaluating Samumed’s investigational compound SM07883 for Alzheimer’s disease has dosed its first participant. The Phase 1 trial (ACTRN12619000327189), taking place in Australia, will assess the ... Read more

April 8, 2019April 8, 2019

Investigational Azeliragon May Lessen Cognitive Decline in Mild Alzheimer’s Disease Patients with Type 2 Diabetes, Analysis Finds

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The investigational therapy azeliragon decreased inflammation and lessened cognitive decline and dementia in patients with mild Alzheimer’s disease and type 2 diabetes, compared with a placebo, according to data from ... Read more

April 3, 2019April 3, 2019

UB-311 Vaccine Safe in Mild Alzheimer’s Patients, Phase 2a Trial Shows

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United Neuroscience’s vaccine candidate UB-311 was safe and well-tolerated in patients with mild Alzheimer’s disease, according to results from a Phase 2a clinical trial. Patients who participated in this trial ... Read more

April 1, 2019April 1, 2019

Antiviral Medicine Could Help Halt Cognitive Decline in Early Alzheimer’s, Preliminary Data Show

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Preliminary data from a Phase 2 study suggests that treating early Alzheimer’s disease patients who are positive for herpes simplex virus with an antiviral medicine may help halt their ... Read more

March 27, 2019March 27, 2019

ALZ-101 Vaccine Fares Well in Preclinical Study of Alzheimer’s Fish

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Alzinova‘s ALZ-101 vaccine — designed to target toxic forms of the amyloid beta protein that drive neurodegeneration in Alzheimer’s disease — was well-tolerated in non-human primates and displayed efficacy in a ... Read more

March 18, 2019March 18, 2019

Dosing Starts in Phase 2 trial of Bryostatin-1 for Alzheimer’s

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Neurotrope Bioscience announced that dosing of patients has started in its Phase 2 clinical trial to further evaluate Bryostatin-1, the company’s investigational candidate for the treatment of moderate to ... Read more

March 15, 2019March 15, 2019

Brains of People with Sleep Apnea Show Increased Tau Protein Aggregates

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People with sleep apnea show increased accumulation of tau protein aggregates — a hallmark of Alzheimer’s disease — in brain regions linked to memory and spatial navigation, a study ... Read more

March 11, 2019March 11, 2019

Manipulating Brain Cells called Astrocytes May Ease Alzheimer’s Symptoms, Study Finds

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Manipulating astrocytes — a type of cell in the brain — to deliver a protein that favors the survival of neurons can rescue cognitive function, including memory, in a ... Read more

March 8, 2019March 8, 2019

Hip Fracture in Older People Without Dementia May Be Sign of Undiagnosed Alzheimer’s

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Abnormal levels of amyloid-beta and tau protein — two hallmarks of Alzheimer’s disease — were detected in the cerebrospinal fluid of older individuals without dementia who were hospitalized for ... Read more

Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Toll of Family Caregiving on Health is Much Smaller Than Previously Reported, Study Suggests

Phase 1 Trial of Alzheimer’s Candidate SM07883 Doses First Participant

Investigational Azeliragon May Lessen Cognitive Decline in Mild Alzheimer’s Disease Patients with Type 2 Diabetes, Analysis Finds

UB-311 Vaccine Safe in Mild Alzheimer’s Patients, Phase 2a Trial Shows

Antiviral Medicine Could Help Halt Cognitive Decline in Early Alzheimer’s, Preliminary Data Show

ALZ-101 Vaccine Fares Well in Preclinical Study of Alzheimer’s Fish

Dosing Starts in Phase 2 trial of Bryostatin-1 for Alzheimer’s

Brains of People with Sleep Apnea Show Increased Tau Protein Aggregates

Manipulating Brain Cells called Astrocytes May Ease Alzheimer’s Symptoms, Study Finds

Hip Fracture in Older People Without Dementia May Be Sign of Undiagnosed Alzheimer’s

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