Posts by: Patricia Inacio, PhD

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Boosting mitophagy — a natural process that clears neurons from damaged mitochondria (cells’ energy powerhouses) — decreased amyloid plaque formation and reversed cognitive deficits, namely memory impairments, across different ... Read more

February 18, 2019February 18, 2019

Anti-epileptic Therapy Not Linked to Increased Dementia Risk, Study Reports

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Use of anti-epileptic therapy is not linked to an increased risk of dementia, according to the results of a real-world study with more than 100,000 patients followed in general ... Read more

February 15, 2019February 15, 2019

HIV Therapy May to Help Stop ‘Jumping Gene’ Linked to Inflammation Associated with Aging

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HIV therapies that block an enzyme that is essential for viruses to replicate, called reverse transcriptase, may offer a new way of treating age-related disorders like Alzheimer’s, a study ... Read more

February 11, 2019February 11, 2019

Brain Metabolism of Hibernating Hamsters May Reveal Novel Therapeutic Targets for Alzheimer’s Disease

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Upon hibernation, the brains of Syrian hamsters undergo metabolic changes that involve the phosphorylation of tau protein — a hallmark of Alzheimers’ disease. However, this process is rapidly reversed upon ... Read more

February 4, 2019February 4, 2019

Alzheimer’s Association Funds 2-Year Extension of Study that Explores Intensive Blood Pressure Treatment on Dementia Risk

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The Alzheimer’s Association has funded a two-year extension of the SPRINT-MIND study — SPRINT MIND 2.0 — to further explore the role of intensive treatment to lower blood pressure and the ... Read more

February 1, 2019February 1, 2019

Genentech Halts Phase 3 Trials Testing Crenezumab for Early Alzheimer’s Disease

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Two Phase 3 trials — CREAD 1 and CREAD 2 — evaluating crenezumab as a therapy for early Alzheimer’s disease have been discontinued, Genentech announced. The decision was based on ... Read more

January 30, 2019January 30, 2019

Epigenetic Therapy Restored Memory, Cognitive Function in Mouse Model of Familial AD

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Using a new type of approach called epigenetics, researchers were able to temporarily rescue memory and cognitive function in a mouse model of Alzheimer’s disease. The study showed that ... Read more

January 28, 2019January 28, 2019

Anti-epileptic Therapies Linked to Longer Hospital Stays in Alzheimer’s Patients, Study Reports

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Alzheimer’s disease patients who take anti-epileptic therapies have a higher number of accumulated days spent in the hospital than those not prescribed this type of medication, a study reports. ... Read more

January 25, 2019January 25, 2019

UB-311 Vaccine Safe, Effective in Mild Alzheimer’s Patients, Phase 2a Trial Suggests

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United Neuroscience’s Alzheimer’s vaccine candidate UB-311 was found safe and well-tolerated, triggering an antibody response against beta-amyloid in most of the patients, according to Phase 2a trial results. “These early results suggest a clinical ... Read more

January 23, 2019January 23, 2019

Stroke Medicine May Prevent Beta-Amyloid Accumulation in Early Alzheimer’s, Mouse Study Shows

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A medicine being developed to treat stroke patients may help protect the brain from Alzheimer’s disease by suppressing the accumulation of toxic amyloid-beta during the early stages of the ... Read more

Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Alzheimer’s Animal Studies Examine Lack of ‘Cleaning’ in Brain Cells

Anti-epileptic Therapy Not Linked to Increased Dementia Risk, Study Reports

HIV Therapy May to Help Stop ‘Jumping Gene’ Linked to Inflammation Associated with Aging

Brain Metabolism of Hibernating Hamsters May Reveal Novel Therapeutic Targets for Alzheimer’s Disease

Alzheimer’s Association Funds 2-Year Extension of Study that Explores Intensive Blood Pressure Treatment on Dementia Risk

Genentech Halts Phase 3 Trials Testing Crenezumab for Early Alzheimer’s Disease

Epigenetic Therapy Restored Memory, Cognitive Function in Mouse Model of Familial AD

Anti-epileptic Therapies Linked to Longer Hospital Stays in Alzheimer’s Patients, Study Reports

UB-311 Vaccine Safe, Effective in Mild Alzheimer’s Patients, Phase 2a Trial Suggests

Stroke Medicine May Prevent Beta-Amyloid Accumulation in Early Alzheimer’s, Mouse Study Shows

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