Posts by: Patricia Inacio, PhD

Biohaven and the Alzheimer’s Disease Cooperative Study (ADCS) have jointly launched a Phase 2 clinical trial for the investigational drug trigriluzole, a glutamate modulating candidate that could potentially improve symptoms in ... Read more

September 13, 2017September 13, 2017

Link Between Lysosomes and Granulins in Brain Cells May Aid Understanding of Alzheimer’s

News

Researchers developed antibodies targeting a group of proteins called granulins, and discovered for the first time that they’re important to the well-being of lysosomes, which are vital organelles linked to neurodegenerative ... Read more

August 22, 2017

Low Serotonin in Brain May Explain Cognitive Impairment, Johns Hopkins Study Shows

News

Johns Hopkins researchers looked at brain scans and discovered that lower levels of the neurotransmitter serotonin underlie the mild loss of cognitive functions that usually precede the onset of Alzheimer’s ... Read more

August 4, 2017

Biomarkers May Help Develop Better and More Personalized Alzheimer’s Treatments, Study Suggests

News

The physical properties of proteins in the spinal fluid and blood of people with Alzheimer’s disease may constitute valuable biomarkers to help diagnose disease progression and predict patients’ outcomes, new research ... Read more

July 20, 2017

New Method Promises to Quickly Identify Abnormal Proteins Involved in Alzheimer’s

News

Researchers developed a new method for capturing proteins implicated in several diseases, including Alzheimer’s. The technique promises to accelerate the identification of altered proteins underlying disease progression (biomarkers). This ... Read more

May 30, 2017

Alzheimer’s Deaths in U.S. Increased 55% in 15-Year Span, CDC Study Reveals

News

In a recent Morbidity and Mortality Weekly Report from the Centers for Disease Control and Prevention (CDC), researchers show that deaths due to Alzheimer’s disease increased almost 55% between ... Read more

May 16, 2017May 16, 2017

Preventing Diabetes May Help Halt Alzheimer’s Progression in New York State, Report Says

News

The state of New York lacks effective measures for preventing diabetes, which is fueling a dramatic increase in Alzheimer’s disease. So says a new document, “Unprevented Diabetes Means Unnecessary Alzheimer’s,” issued by Health ... Read more

May 8, 2017

ALZ-801 Works Against Alzheimer’s by Preventing Protein Component Clumping, Study Reports

News

The Alzheimer’s therapy ALZ-801 works by preventing protein components from clumping together to trigger the amyloid plaque accumulation in the brain that causes the disease, researchers say. Disease-modifying drugs for Alzheimer’s ... Read more

May 3, 2017

‘Memory Protein’ NPTX2 Underlies Cognitive Decline in Alzheimer’s, Researchers Find

News

Memory loss and cognitive dysfunction, two hallmarks of Alzheimer’s disease, have now been linked to low levels of one particular protein, called NPTX2. The discovery represents a stepping-stone in ... Read more

March 14, 2017

Diabetes Therapy Symlin Could Lead to Faster Diagnostic Tests for Alzheimer’s

News

The diabetes drug Symlin (pramlintide) may help scientists develop novel and faster diagnostic tests for Alzheimer’s disease (AD), a study indicates. The research, “An amylin analog used as a ... Read more