The latest clinical data from Genentech on crenezumab and gantenerumab demonstrate the investigational therapies' potential to reduce amyloid aggregates in Alzheimer’s disease patients. Trial results were discussed in several presentations at the 2018 Alzheimer's Association International Conference (AAIC), recently held in Chicago. “The range of data that Roche and Genentech are presenting at AAIC is a testament to our commitment to bring new treatments to help the many millions of people living with Alzheimer’s disease,” Sandra Horning, MD, chief medical officer and head of global product development at Roche, said in a press release. One of the hallmarks of Alzheimer’s disease is the formation of protein plaques and tangles between nerve cells. These are made of beta-amyloid fragments that stick together and accumulate between nerve cells, disrupting their function.