Alzheimer’s Research UK Funds Manchester University Project on Alzheimer’s Brain’s Molecular Map

Alzheimer’s Research UK Funds Manchester University Project on Alzheimer’s Brain’s Molecular Map
A research project designed to create a molecular map with thousands of proteins in the brain with Alzheimer's disease, conducted by Dr. Richard Unwin, from The University of Manchester and Central Manchester University Hospitals NHS Foundation Trust has been granted a £30,000 ($48,600 dollars) award by Alzheimer’s Research UK. The project is expected to start this month, which is also World Alzheimer’s Month. “I’m really pleased to have won this award, which will support an important new project in my laboratory. We’ve already started to study the metabolism of seven different areas of the brain in Alzheimer’s, that is the chemical reactions that generate the energy brain cells need to work, and we see some important changes associated with the development of the disease," explained lead researcher Dr. Richard Unwin, who also works at the Centre for Advanced Discovery and Experimental Therapeutics (CADET). The researcher believes that the new funding will enable him to expand his research "by looking at thousands of proteins in the brain to get even more detailed information about how these changes are controlled, and how the brain is working." He expects that the project will ultimately provide data to create detailed maps of how Alzheimer’s affects the human brain. Dr. Unwin will now start his work by examining how the disease affects the biology of different areas of the human brain, by mapping the relative amounts of over 3,000 proteins in the brain. The main purpose is to study its biology in detail, which is possible since he will analyze donated tissue from both Alzheimer's patients and healthy patients. Unwin expects to improve the data about the brain, since currently most of the insight into brain activity comes from brain scans,
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