Novel Culture System Replicates Alzheimer’s Disease Development; Confirms Amyloid Hypothesis; Should Significantly Reduce Drug Development Time/Cost

Novel Culture System Replicates Alzheimer’s Disease Development; Confirms Amyloid Hypothesis; Should Significantly Reduce Drug Development Time/Cost
An innovative laboratory culture system developed by an international team of investigators led by scientists of the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH) provides the first clear evidence supporting the hypothesis that deposition of beta-amyloid plaques in the brain is the first step in a cascade of events underlying development of Alzheimer's disease (AD). Using a novel three-dimensional culture system, the Mass. General scientists have succeeded, for the first time, in reproducing the full course of the devastating neurodegenerative disease's development, and also identify the essential role in that process of a particular enzyme, th
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