Clues To The Genetics of Memory Function in Elderly Revealed in New Study

Clues To The Genetics of Memory Function in Elderly Revealed in New Study
Memory FunctionA large study entitled “Genome-wide studies of verbal declarative memory in non-demented older people: the CHARGE consortium” was recently published in the journal Biological Psychiatry and sought to identify the genetics of memory function in older individuals. One of the most essential aspects of human cognition is the ability to form and retrieve memories. In late life, severe cognitive decline in memory is one of the early signs of dementia. The conscious recall of information and its verbalization is called verbal declarative memory, and delay in this task has been found in studies to be a strong predictor of Alzheimer disease. Additionally, evidence shows that there is a genetic component in verbal memory performance, however, there is a lack of studies showing consistent results in which genetics are effectively associated. Three genome-wide association studies (GWAS) with young people found associations of genetic variants in the KIBRA and CTNNBL1 genes with verbal declarative memory delayed recall.  However, there is a lack of GWAS studies invol
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