Insulin Nasal Spray Improves Alzheimer’s Cognitive Impairment, Study Shows

Insulin Nasal Spray Improves Alzheimer’s Cognitive Impairment, Study Shows
insulin nasal sprayA research team from the Wake Forest Baptist Medical Center developed a form of insulin intended to be delivered via nasal spray that can have positive results on mental capabilities, such as the working memory of adults suffering from Alzheimer's disease and other mental and cognitive impairments. The study examined the nasal spray's effects on 60 adults diagnosed with amnesic mild cognitive impairment (MCI) or mild to moderate Alzheimer's disease (AD). They received via the intranasal route 40 international units (IU) of insulin detemir, a man-made form of the hormone, over 21 days. The results evidenced improvement in their capabilities of retaining and processing both verbal and visual information when compared to those patients that only got 20 IU or none (placebo). Further, the patients with the APOE-e4 gene, a gene that is known to increase the risk of developing Alzheimer's, that received 40 IU doses also recorded significant improvements in memory, compared to those who were given lower doses or the placebo; the non-carriers of the gene r
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