USC Study Discovers Potential Early Sign of Alzheimer’s Disease

USC Study Discovers Potential Early Sign of Alzheimer’s Disease
A research article, titled, "Blood-Brain Barrier Breakdown in the Aging Human Hippocampus" published in the journal Neuron by a team of investigators from the Zilkha Neurogenetic Institute (ZNI) at the University of Southern California (USC) Keck School of Medicine used high-resolution MRI analysis to evaluate the regional permeability of the blood brain barrier (BBB) in the living human brain. The study looked at the age dependent breakdown in regions of the brain that are considered critical for both learning and memory, and are also shown to be affected early in patients diagnosed with Alzheimer’s disease (AD). AD is a neurological disease that causes patients to have debilitating declines in brain function. It affects a patient’s memory, thinking, and cognitive reasoning skills. According to the CDC, as many as 5 million Americans are suffering from AD. The symptoms of the disease often first appear after age 60, and the risk for diagnosis increases substantially with age. It
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