Exposure to Electromagnetic Fields Delays the Development Alzheimer’s Disease Rat Model

Exposure to Electromagnetic Fields Delays the Development Alzheimer’s Disease Rat Model
Findings from a recent study conducted by a team of researchers in China indicate that certain conditions of exposure of extremely low frequency electromagnetic fields could delay the development of Alzheimer’s’ Disease (AD) in rats. The study was published in the journal PLOS One. Extremely low frequency electromagnetic fields (ELF-EMF) are generated mostly by electric equipment, such as high voltage transmission lines, transformer substations, motors, and household appliances, with a frequency ranging from 0 to 300 Hz. Alzheimer's disease (AD) is an age-related progressive neurodegenerative disease characterized by progressive memory loss and a decline of cognitive function. The characteristic pathological changes of AD mainly include differing degrees of neuronal loss or apoptosis, senile plaques (SP) formed by extracellular deposits of amyloid-β (Aβ), and intracellular neurofibrillary tangles (NFT) constituted by hyperphosphorylated microtubule-associated protein tau (Tau) in the brain. Although some epidemiological investigations have shown a potential association between long-term exposure of ELF-EMF and AD, few correlated animal experiments have been reported and no understood mechanism can reasonably explain this association. There is evidence from AD animal models studies regarding the possible mechanisms of AD, with studies showing that D-galactose can cause premature aging and organ decline, and the intracerebral injection of Aβ25–35 peptide fragments can induce AD-like clinicopathologic features. In the study titled “
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