Major Discovery May Alter Thinking on Alzheimer’s Disease

Major Discovery May Alter Thinking on Alzheimer’s Disease
Investigators at the Blancette Rockefeller Neurosciences Institute (BRNI) recently discovered that the most significant genetic risk factor associated with Alzheimer’s disease, the Apolipoprotein E4 (ApoE4) gene, leads to a decrease in brain synapses, which occurs frequently prior to the onset of amyloid plaques or tangles developing in Alzheimer’s patients. This discovery may alter the paradigm, treatment and prevention of the disease.

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One comment

  1. Ed Martinez says:

    Eureka. Finally out of the amyloid trap. Ever since learning about histones and their proximity to DNA I had a hunch that gene activation by their folding or misfolding could was probable.

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