- Prion protein: is a protein that can fold in multiple, structurally distinct ways, at least one of which is misfolded and transmissible to other prion proteins.
- Protein aggregate: is a biological phenomenon in which misfolded proteins accumulate and clump together.
- Synapse: is the space where nerve cells connect to one another. When a charge reaches a synapse, it may trigger release of tiny bursts of chemicals called neurotransmitters which are vital components for normal functioning of the brain.
Researchers from Columbia University Medical Center (CUMC) have released multiple study findings showing that long term memories are stored with the help of prion-like proteins called CPEB. These CPEB proteins work to form long term memory in the same way as the mechanisms that cause mad cow disease, kuru, and other degenerative brain diseases. Background Terminology: