Type 2 Diabetes May Contribute Towards Dementia Development

Type 2 Diabetes May Contribute Towards Dementia Development
In a newly published paper in the Neurology journal entitled "Type 2 diabetes mellitus and biomarkers of neurodegeneration", scientists from Australia found that neurodegenerative disease related dementia could be linked to type 2 diabetes. Neurodegenerative disorders occur as a consequence of a progressive loss of structure/function of neurons that lead to the death of nerve cells. This results in diseases like dementia, of which the most known form is Alzheimer’s disease. Patients suffering from dementia may experience difficulties dealing with memory loss, language, impaired visual-spatial orientation, lack of attention and loss of problem solving skills. Various causes of the neurodegeneration processes have been pointed out including genetic mutations, aggregation of proteins, membrane damage, accumulation of intracellular toxic proteins, axonal transport, and mitochondrial dysfunction. However, little is known about the mechanisms of action and influence of preexistent medical conditions like diabetes on neurodegenerative processes. This recent study led by Australian scientists shed some insights into the link between type 2 diabetes and dementia. The team explored whether type 2 diabetes promotes the buildup of amyloid plaque (called β-amyloid) seen in Alzheimer’s disease. The study analyzed data from the US Alzheimer’s Disease Neuroimaging Initiative which involved 816 people with an average age of 74 years. Among those, 397 suffered from mild cognitive impairm
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *