Synaptic Loss Precedes Alzheimer’s Symptoms and Drives Disease, New Study Finds

Synaptic Loss Precedes Alzheimer’s Symptoms and Drives Disease, New Study Finds
Before any signs of cognitive decline start showing, neuronal synaptic connections are lost in mice destined to develop Alzheimer’s. New research shows that microglia – brain immune cells – destroy synapses in a fashion resembling processes in the developing brain, suggesting that it might be possible to develop drugs targeting disease at far earlier stages.

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