Traumatic Brain Injury Linked to Parkinson’s But Not Alzheimer’s in Large Study

Traumatic Brain Injury Linked to Parkinson’s But Not Alzheimer’s in Large Study
Ever since Dr. Bennet Omalu, who Will Smith portrayed in the movie "Concussion," released his 2005 study — based on autopsy results from a former professional football player — that revealed “neuropathological changes consistent with long-term repetitive concussive brain injury,” the future cognitive impact of traumatic brain injury (TBI) has  become a keen interest in the field of clinical neurology and public health. Research focused on TBI and the subsequent associated loss of consciousness (LOC) has suggested that there is a link between these injuries and the decline of brain function, but very few studies show a definitive correlation between TBI with LOC and the future development of either Parkinson’s or Alzheimer’s disease. To fill this data “gap,” researchers from Mount Sinai conducted a study of head injury data from 7,130 older adults, free of dementia at baseline, to investigate associations between TBI and late-life clinical outcomes, such as dementia, Alzheimer’s disease, mild cognitive impairment, and Parkinson’s disease. Data were accrued from 1994 to April 1, 2014. Results showed an association between TBI in some individuals — those who had lost consciousness after injury for more than hour — and Parkinson's disease, but not Alzheimer's. The study, “Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathol
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