Alzheimer’s Researchers Build Mock Protein That Might Help Them Understand Disease

Alzheimer’s Researchers Build Mock Protein That Might Help Them Understand Disease
Researchers at the University of Sussex in England have built a protein closely resembling amyloid-β, except for the fact that it is not capable of aggregating. The new protein, described in a report titled, "A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration," published in the journal of Scientific Reports, will allow researchers to understand the details of how amyloid-β misfolds and accumulates — triggering processes toxic to nerve cells. Studies in lab dishes and animals suggest that once that the amyloid protein starts clumping together in what scientists refe
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