Steps Taken by Amyloid Beta to Enter and Kill Nerve Cells Seen in Study

Steps Taken by Amyloid Beta to Enter and Kill Nerve Cells Seen in Study
One of the pathological hallmarks of Alzheimer's disease is the accumulation of the protein, amyloid beta, in neurons, leading to the formation of plaques that impair brain function. Exactly how amyloid beta enters and becomes toxic to neuron, or nerve, cells, however, is a matter of debate — with a new study suggesting that that the protein leads to toxicity when it changes its structure in order to enter the neurons. The study “Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity” was published in the journal Biological Chemistry. Researchers found evidence that amyloid beta binds to the cell membrane,
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