Genervon Shares Alzheimer’s Gene List Linked to Its GM6 Treatment

Genervon Shares Alzheimer’s Gene List Linked to Its GM6 Treatment
Genervon Biopharmaceuticals recently shared a previously confidential list of 84 genes linked to Alzheimer’s disease which are modulated by their investigational treatment GM6. The move to make the list public was based on a wish to encourage more neurological scientists to investigate broader, multi-target approaches to treat diseases such as Alzheimer’s and ALS (amyotrophic lateral sclerosis). The list was shared with fellow researchers at the JP Morgan Healthcare Conference Jan. 9-12 in San Francisco and is available as a poster on the F1000Research website. Genervon's therapy candidate GM6 is the result of a focused search of master regulators of embryonic development. The protein factor, which constitutes the active site of a larger protein called human motoneuronotrophic factor (MNTF), exists naturally in the body. Genervon’s studies show that the small protein can cross the blood-brain barrier. The company explored the protein for multiple neurological diseases in addition to Alzheimer’s. Genervon has also shared lists of genes related to Parkinson’s disease and ALS. The factor controls numerous genes in the development of the nervous system, but is also involved in monitoring distress signals and coordinating responses to restore homeostasis, according to the company.
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