UsAgainstAlzheimer’s Proposes Key Measures to Advance Treatment Development

UsAgainstAlzheimer’s Proposes Key Measures to Advance Treatment Development
As the disappointment over the failure of solanezumab begins to wane, George Vradenburg, co-founder and chairman of UsAgainstAlzheimer's, seeks to address the efforts needed to continue research and clinical development for Alzheimer’s disease. Despite the inability of Eli Lilly to bring the goods to the table, Vradenburg applauded Lilly’s efforts in the open letter, along with that of patients and caregivers who contributed to the solanezumab trials. The studies, he argued, brought valuable knowledge that will help any future drug development efforts. Vradenburg specifically pointed to a number of factors that he believes are crucial. First, he stated that Alzheimer’s is a disease that needs aggressive treatment. Comparing Alzheimer’s to cancer, he suggested that affected patients and their families are prepared to take the consequences of more aggressive treatments if they can reap the benefits of a slowed or prevented disease progression. Second, he stated that the current approach to Alzheimer’s clinical trials makes a system in which the time before a drug can become available to the patients become unacceptably long. The failure of past trials has made developers target increasingly earlier disease stages. But these trials become both costly and lengthy, with an estimated time to completion of up to eight years. The UsAgainstAlzheimer’s chairman emphasized that even if such a trial become successful in producing a drug, healthcare payers, such as Medicare, may not want to pay for the treatment until they have "real-life" evidence of
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