Potential Treatment, ALZ-801, Shows Efficacy in Early Alzheimer’s Patients with Risk Gene

Potential Treatment, ALZ-801, Shows Efficacy in Early Alzheimer’s Patients with Risk Gene
ALZ-801 may be a safe and effective treatment for Alzheimer’s patients with mild disease who carry two copies of the APOE4/4 gene, results of a clinical program indicate. The results are being disclosed in four presentations by the drug's developer, Alzheon, at the 13th International Conference on Alzheimer’s and Parkinson’s Disease, taking place March 29–April 2 in Vienna. ALZ-801 and its active molecule, tramiprosate, are designed to inhibit the toxic aggregation and accumulation of beta-amyloid plaque between nerve cells, a hallmark of Alzheimer’s disease, to protect neurons. “We are pioneering a precision medicine approach to Alzheimer’s disease with our pivotal program for ALZ-801, by focusing on a well-recognized, genetically defined subset of Alzheimer’s patients with the APOE4 [gene] and by targeting patients at an early point in their disease progression, who have shown the greatest response to our lead molecule,” Martin Tolar, MD, PhD, and Alzheon’s founder, president, and CEO, said in a
Subscribe or to access all post and page content.