Recent History of Psychiatriac Disorders May Be Risk Factor for Alzheimer’s Disease

Recent History of Psychiatriac Disorders May Be Risk Factor for Alzheimer’s Disease
A nationwide case-control study conducted by researchers from the University of Eastern Finland found an association between mental and behavioral disorders and Alzheimer's disease (AD). However, this effect was dependent on the time between the first signs of  psychiatric disorders and the diagnosis of Alzheimer's. The study, "Hospital-treated mental and behavioral disorders and risk of Alzheimer’s disease: A nationwide nested case-control study," was published in the journal of the European Psychiatric Association (EPA), European Psychiatry. Previous studies have tried to understand whether psychiatric disorders could be associated with Alzheimer's development and progression. However, the use of different methodologies has generated mixed results and inconsistent findings. “Identification of potential AD/dementia risk factors is important, because it may aid in targeting or developing potential strategies to prevent or delay the dementia onset,” the researchers wrote. The study was based on the Finnish Medication and Alzheimer’s disease (MEDALZ) study, which includes all 70,719 community-dwelling residents of Finland who were diagnosed with Alzheimer's between 2005 and 2011. The authors compared the clinical history of psychiatric disorders, extracted from the Finnish Hospital Discharge Register, of 1,932 Alzheimer's patients and compared them to those of 1,784 age- and gender-matched controls. The authors found that a history of mood disorder, such as depression, or a be
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