Aquinnah Receives $10M in New Support to Develop Therapies for Alzheimer’s and ALS

Aquinnah Receives $10M in New Support to Develop Therapies for Alzheimer’s and ALS
Aquinnah Pharmaceuticals has received $10 million from two pharmaceutical companies, Pfizer and AbbVie, to advance its treatments for amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and other neurodegenerative diseases toward clinical trials. Together with a previous investment from Takeda Pharmaceuticals, Aquinnah's research and development support totals $15 million. "We are excited to have the support of three world-class pharmaceutical companies to expand our drug development efforts from ALS into new RNA binding proteins known to modulate Tau, one of the hallmark pathological proteins involved in Alzheimer's disease," Glenn Larsen, Aquinnah's president and chief executive officer, said in a press release. Many therapeutic approaches for neurodegenerative diseases focus on targeting neurofibrillary tangles and beta-amyloid plaques. Although these are major features of ALS and Alzheimer’s, other elements are common in these diseases. "There continues to be a substantial need to combat neurodegenerative diseases like Alzheimer's disease and ALS," said Scott Brun, Vice president, Scientific Affairs and Head at AbbVie Ventures. "Aquinnah's research approach … could offer valuable advances to treat these debilitating, progressive brain diseases and complements AbbVie's ongoing neuroscience research efforts." Aquinnah is targeting complex structures of proteins and RNA molecu
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