Enzyme Slices Off Protein Chunks That End up Toxic, Contributing to Parkinson’s and Alzheimer’s, Study Reports

Enzyme Slices Off Protein Chunks That End up Toxic, Contributing to Parkinson’s and Alzheimer’s, Study Reports
An enzyme called asparagine endopeptidase contributes to Parkinson’s as well as Alzheimer's by slicing off fragments of proteins that end up being toxic, a study reports. Previous researched showed that the enzyme, also known as AEP, plays a role in Alzheimer’s. The new study indicates it plays a role in Parkinson’s, too. The research, “Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease,” was published in the journal Nature Structural and Molecular Biology. An accumulation of faulty pr
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