Can Brain Bacteria Contribute to Alzheimer’s? These Researchers Think So

Can Brain Bacteria Contribute to Alzheimer’s? These Researchers Think So
Patients with Alzheimer’s disease may have more bacteria — and different types — in their brains, compared to the general population, according to results of a new study. These findings support that bacterial infection and inflammation may contribute to the development of this devastating disease. The study is titled “16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer’s Post-Mortem Brain” and was published in the journal Frontiers in Aging Neuroscience. Neuroinflammation is one the mechanisms known to be active in Alzheimer’s disease. This reflects the body’s response to eliminate toxic factors, but too much of it ends up killing neurons. "Alzheimer's brains usually contain evidence of neuroinflammation, and researchers increasingly think that this could be a possible driver of the disease, by causing neurons in the brain to degenerate," David Emery, the study’s first author, said in a press release. According to Emery, this inflammatory response may be caused by the presence of bacteria in the brain. In a normal brain, this would not happen because of the meninges, the three tissue layers that protect the brain by regulating which molecules go in and out. However, in the Alzheimer’s brain, certain blood vessels lose their integrity, allowing bacteria to enter and settle in. "Previous studies looking at bacteria in the Alzheimer's brain have primarily investigated specific bacterial species," said Shelley Allen, another study author. "We wanted to use an unbiased method to obtain the fu
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2 comments

  1. Luis Goitia says:

    So according to this study the disesase can be contagious from one individual to another, interchanging bacterias?

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