Inhibiting HDAC2 Enzyme May Stop Memory Loss

Inhibiting HDAC2 Enzyme May Stop Memory Loss
A research team from MIT has found a way to reverse memory loss in mice, which may lead to new treatments for patients with Alzheimer's disease. The findings were reported in a study titled “The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons” and published in the journal Cell Reports. The method focuses on the interactions of the SP3 gene with an enzyme named HDAC2, which can turn genes off that are essential for creating new memories. This process contributes to the formation of a genetic blockade in the brains of patients with Alzheimer's disease and leads to cognitive decline. “If we can
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3 comments

    • Tim Bossie says:

      Thank you for the question Susan. We wish we could give you an answer, but we are monitoring this and will update as soon as we know more information.

  1. Lic. phil. Irene Zbinden-Birchmeier says:

    Dear Mr. Bossie

    I have the same question like Susan Finger. My husband suffers under loosing memory. And I am very interesting to know when this compound is produced for human beings. I hope for Aducanumab or other compounds so my husband can live a better life. If science points in Switzerland are available for HDAC2, please let my know.

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