2 Separate Studies Show How Rare Mutation on TREM2 Gene Contributes to Alzheimer’s

2 Separate Studies Show How Rare Mutation on TREM2 Gene Contributes to Alzheimer’s
Researchers of two independent studies have discovered how a specific mutation on the TREM2 gene contributes to the development and progression of Alzheimer’s disease, findings that shed light on the role of TREM2 in the brain, and can lead to new ways of treating this neurological disease. Their work was reported in studies titled “TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer’s disease-associated H157Y variant” and “An Alzheimer associated TREM2 variant occurs at the ADAM cleavage site and affects sheddin
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