Biogen, Citing New Phase 1 Data, Says Aducanumab Reduces Amyloid Plaques in Alzheimer’s

Biogen, Citing New Phase 1 Data, Says Aducanumab Reduces Amyloid Plaques in Alzheimer’s
Aducanamab helps reduce amyloid plaques in Alzheimer’s patients who receive a gradually increasing dose of the therapy, its developer, Biogen, reports, citing results from the long-term extension of its ongoing Phase 1b study (NCT01677572). The potential treatment, also known as BIIB037, is a human monoclonal antibody derived from healthy elderly patients who have no signs

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2 comments

  1. Alzheimer’s disease and CADASIL are heritable, adult-onset dementias that both involve damaged small blood vessels.
    As I sit each morning, reading articles in reference to Alzheimer’s I become more discouraged that they haven’t found a treatment or cure for this brain disease after all these years with research and wasted funds.
    Now that Bill Gates is involved let’s hope they make progress for the young ones and get it right.
    Alzheimer’s disease and CADASIL are heritable, adult-onset dementias that both involve damaged small blood vessels.
    Theory #1: With young on set dementia on the rise worldwide. Could the amyloid plaques and tau tangles be connected to a mutation from CADASIL’s, chromosome 19 notch 3 gene. Which is causing the Alzheimer’s brain to go haywire?

    Theory #2: Silent Strokes at any age: Patients unaware they even had one, causes damage to the brain. Affects the thought process, mood, and cognitive functions and may lead to loss of urinary bladder control. So does that mean silent strokes over the years could also lead to young onset dementia?

    This is just a thought: for all medical professionals, be a little more compassionate and inquire about the family history not only physical
    ailments, you need information on the characteristic personality family traits from childhood, which also holds a lot of information. There are more young ones being diagnosed with dementia, it’s not the old person’s disease anymore and you just don’t wake up one day with dementia.

  2. Georges Tony MARCEL,,MD,PhD says:

    It is true that Aducanumab clears amyloid plaques, which is perfecly useless. Adults above 7O frequently have plaques, without Alzheimer!
    The danger of clearing them is freeing small toxic oligomers,which Biogen has NOT disproved.

    Tony Georges MARCEL, MD, PhD

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