No Clear Way Forward Seen in Attempts at Avoiding Dementia in Older Age, Review Says

No Clear Way Forward Seen in Attempts at Avoiding Dementia in Older Age, Review Says
Four ways of possibly preventing dementia late in life — prescription medicines, over-the-counter (OTC) supplements and vitamins, physical activity, and cognitive training — are all seem to be inadequate at that task, a Minnesota Evidence-based Practice Center (EPC) study showed. Researchers conducted a systematic review of published to determine if any interventions had enough evidence to warrant an official recommendation in any of these four therapeutic  by the Agency for Healthcare Research and Quality (AHRQ), part of the U.S. Department of Health and Human Services. Their separate studies — one in each of these areas — were published in the Annals of Internal Medicine. While the prevalence of dementia and Alzheimer’s disease is expected to increase as the population ages, there are no optimal treatments to prevent or delay cognitive decline. Data in a review of 51 clinical studies comparing the effect of prescription medication with placebo, usual care, or active control on cognitive outcomes, was not sufficient to support use of any of the studied pharmacological options. These included medications for dementia, hypertension, diabetes and products for cognitive protection. The results were published in "Pharmacologic Interventions to Prevent Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer-Type Dementia: <
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3 comments

  1. Edward Wollmann says:

    The major problem with these types of ‘reviews’ is that the studies they had reviewed usually had clinical interventions that were not long enough in duration in order for them to be deemed truly effective.

    My suggestion would be; if an intervention such as physical activity has proven itself to be beneficial in a variety of settings over a wide expanse of time, then chances are it will work in a setting such as Alzheimer’s or dementia as well.

    Bottom line: don’t wait for definitive “proof” to come from clinical trials or such ‘systematic reviews’ because we’ll all be dead before then.

  2. More evidence that the “mainstream approach” to preventing and/or curing Alzheimer’s is not on the right track. We need to change our thinking about this disease and take a look at strong scientific evidence that is out there. Avoiding aluminum and removing aluminum from our bodies and brains is the way to prevent Alzheimer’s. Research has reached a tipping point and Aluminum is a causal factor of Alzheimer’s. Drinking silica water has been shown to improve cognition in people with Alzheimer’s. Take a look at a video my husband Dennis N Crouse and I made it will change the way you think about Alzheimer’s. https://www.youtube.com/watch?v=uGmYsFPHguA

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