CTD and Kerwin Center Discussing Partnership on Cholesterol-Lowering Therapies for Alzheimer’s

CTD and Kerwin Center Discussing Partnership on Cholesterol-Lowering Therapies for Alzheimer’s
CTD Holdings and the Kerwin Research Center are discussing working together on the use of cholesterol-lowering therapies called cyclodextrins as possible treatments for Alzheimer’s disease. Cyclodextrins are non-toxic compounds made up of sugar molecules that can bind with and extract cholesterol. Preclinical-trial studies in Niemann-Pick disease and Alzheimer’s show they can protect nerve cells, suggesting they can become a potential therapy for the disorders. Scientists know high cholesterol is a risk factor for Alzheimer’s. They also know that cholesterol-lowering drugs reduce the progression of the disease. This may be because cholesterol and membrane lipid proteins can control the production of the harmful beta-amyloid protein associated with Alzheimer's. "More than 25 million people globally suffer from dementia, most with Alzheimer's disease,” Sharon Hrynkow, CTD's senior vice president for medical affairs, said in a press release. “With no cure, few treatment options, and the number of elderly people globally expected to reach 1 billion by the year 2030, there is an urgent need for new treatments to combat this devastating disease." CTD was the first company to use cyclodextrin-based products as a therapy for conditions that involve mental deterioration. Its lead product, Trappsol Cyclo, has received orphan drug status in the United States and Europe. The designation is aimed at accelerati
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