Largest Genetic Database on Alzheimer’s Disease Will Soon Be Available to Researchers

Largest Genetic Database on Alzheimer’s Disease Will Soon Be Available to Researchers
The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS), the largest genetic database on Alzheimer’s disease, will soon begin to make large sets of DNA sequences available to researchers. Analysis of these large sets of genomic data may help identify genetic risks and protective factors for Alzheimer’s disease. The announcement was made during the July 2018 Alzheimer’s Association International Conference in Chicago. The first release of the database will contain the entire DNA sequence (whole genome sequence) of up to 5,000 people, including Alzheimer’s patients and healthy control subjects of European, Caribbean Hispanic and African-American descent. Within a year, information from 20,000 more people will be added. The data will be managed by the Genomic Center for Alzheimer’s Disease (GCAD) at the Perelman School of Medicine (Penn Med) at the University of Pennsylvania, Philadelphia. This institution will be responsible for processing all DNA sequences and patient characteristics from all the sources of information, in a process called harmonization, to help researchers analyze big sets of data stored. NIAGADS and GCAD are directed by Gerard Schellenberg and Li-San Wang, PhDs and professors of pathology and laboratory medicine at Penn Med. “Genetic findings for Alzheimer’s disease are critical for identifying targets for therapeutic development,” Wang said in a press release. “Making these data
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