Dysregulation of Iron Could Play a Central Role in Development of Early Onset Alzheimer’s

Dysregulation of Iron Could Play a Central Role in Development of Early Onset Alzheimer’s
Iron dysregulation in the brains of patients with early onset of Alzheimer’s disease (EOfAD) plays a central role in disease development and progression, according to a new theory. The study, “Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer’s Disease,” was published in the journal Frontiers in Neuroscience. Iron, the most abundant transition metal in the human body, plays a key role in the production of energy by the mitochondria — the compartment of the cell responsible for meeting all of the cell’s energy needs. A charged version of iron, called Fe2+
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