Protein Involved in Calcium Transport in Nerve Cells Linked to Alzheimer’s in Early Study

Protein Involved in Calcium Transport in Nerve Cells Linked to Alzheimer’s in Early Study
A protein that's involved in calcium transport within nerve cells was linked to sporadic Alzheimer's disease by scientists working in Spain. This protein, called STIM1, may hold promise as a biomarker of this common and non-familial form of Alzheimer’s. Importantly, common treatments for hypertension that are based on dihydropyridine — and known as calcium channel blockers — were seen to halt nerve cell death in a laboratory setting. The study, “STIM1 deficiency is linked to Alzheimer’s disease and triggers cell death in SH-SY5Y cells by upregulation of L-type voltage-operated Ca2+ entry,” was published in the
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