AxoSim Licenses Mini-Brain Technology to Pursue Therapies for Alzheimer’s, Other Disorders

AxoSim Licenses Mini-Brain Technology to Pursue Therapies for Alzheimer’s, Other Disorders
AxoSim has acquired exclusive rights to lab-grown brain miniatures, coined “Mini-Brain,” a technology developed at Johns Hopkins University that uses stem cells to create models of the human brain in a dish. The technique may help speed therapy discovery for many neurological diseases, including Alzheimer's disease. "Acquiring rights to the intellectual property underlying the Mini-Brain technology is a major step forward in our drive to transform neurology drug research," Lowry Curley, PhD, CEO of AxoSim, said in a press release. "The Mini-Brain technology complements our innovative Nerve-on-a-Chip platform and accelerates our strategy of providing the broadest and most scientifically robust neuroscience models to our growing roster of biopharmaceutical partners," he said. This organoid-based technology was developed by Thomas Hartung, MD, Johns Hopkins Bloomberg School, and collaborators to create an alternative to animal testing. The Mini-Brain platform uses human adult cells (most often skin cells) that are grown and reprogramed in the lab to return to an undifferentiated, stem cell-like state. Using specific cockta
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