Cure Alzheimer’s Fund Reaches $100 Million Milestone

Cure Alzheimer’s Fund Reaches $100 Million Milestone
In awarding more than $100 million to support scientific efforts to prevent, slow or reverse Alzheimer’s disease, the nonprofit Cure Alzheimer’s Fund has reached a significant milestone. Since its founding, the 15-year-old organization has backed some 425 novel projects conducted by 170 investigators worldwide. Those projects have resulted in the publication of more than 525 peer-reviewed research papers, and in breakthroughs that could lead to development of innovative Alzheimer's treatments. Of late, the organization said, there has been major interest in studies involving the permeability of the blood-brain barrier — the semipermeable membrane that protects the brain against the external environment, and is a major barrier for the efficient delivery of certain therapeutics that need to reach the brain and central nervous system. A new Cure Alzheimer's-supported initiative, the Berg Brain Entry and Exit Consortium, is fostering multi-institutional partnerships focused on the relationship between cerebrovascular function and neuroimmune activation and resolution, sparking prospective new ways to develop and deliver therapies that can cross the blood-brain barrier. The organization also cited as one of Cure Alzheimer's top breakthroughs the Alzheimer’s Genome Project, the first large-scale, family-based study of the human genome
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