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Elder Rage: How to Survive Caring for Aging Parents is a new book by Jacqueline Marcell, who details her experiences caring for her elderly parents, both of whom had Alzheimer’s disease. She has written the book as an aid to other caregivers. Initially, both her parents were undiagnosed. Marcell describes the struggle in her book:…

Progressive supranuclear palsy is a brain disease that causes difficulty with walking, balance, and eye movements. The nonprofit CurePSP is dedicated to finding treatments and a cure for the disease, but its mission also extends beyond PSP. By initiating clinical trials to study PSP as well as head injury due to concussion,…

CurePSP is a Maryland-based nonprofit organization that focuses on neurodegenerative diseases that strike when people are in their 50s to 70s, including Alzheimer’s disease. PSP stands for progressive supranuclear palsy, which is a neurodegenerative disorder that impacts movement, walking, speech, balance, mood, vision, behavior, and cognition. Like Alzheimer’s, PSP is characterized by…

A new study out of Michigan points to the pro nerve growth factor (proNGF) as a possible biomarker that could aid in the diagnosis of early Alzheimer’s disease (AD). The article, “Cerebrospinal fluid proNGF: A putative biomarker for early Alzheimer’s disease,“ appeared in the journal…

It is widely accepted that exercise is good for your health, but can it even increase brain cells? That is the conclusion from several new reports published in the first issue of the journal Brain Plasticity. Overall, the publications presented several pieces of compelling evidence revealing that exercise benefits the brain,…

Everyone knows that exercise is good for you, both physically and mentally. Now, a new study suggests that physical activity may not only boost brainpower, it might even prevent Alzheimer’s disease. Researchers from St. Louis, Missouri, studied mice with an experimental form of Alzheimer’s disease and found that those mice doing the…

Sometimes more is not necessarily better. This may especially be true of Alzheimer’s disease clinical studies, too many of which have been tried and failed, leading top scientists to question their design and execution. Better planning in the application of more promising approaches might make more sense — and improve a…

U.K. researchers, headed by the Institute of Psychiatry, King’s College London, have found that donepezil administered during the later stages of Alzheimer’s might temporarily decrease the likelihood that someone will need to move into a nursing home. The study report, entitled “Nursing home placement in the Donepezil and…

Scientists at Massachusetts General Hospital (MGH) have published a new study describing how neurofibrillary tangles — one of the hallmarks of Alzheimer’s disease — develop. Alzheimer’s disease is characterized by a progressive degeneration of specific brain regions, starting with those areas involved in memory. Two proteins are found at…

New research presented during the 14th International Conference on Endothelin: Physiology, Pathophysiology and Therapeutics, focused on the effects of IRL-1620 in a rat model of Alzheimer’s disease (AD). The compound, which acts on the endothelin B (ETB) receptor, reduced learning and memory deficits and oxidative stress in the animals, showing potential as an AD…