Anavex Life Sciences Corp. reported that a positive dose-response relationship has been observed in its ongoing Phase 2a clinical trial of ANAVEX 2-73 as a potential treatment for mild-to-moderate Alzheimer’s disease (AD). The announcement came as part of a planned, interim study analysis. The ANAVEX 2-73 Phase 2a study is a multicenter trial…
Tetra Discovery Partners, in collaboration with the NIH Blueprint Neurotherapeutics Network, announced the start of Phase 1 safety trials of BPN14770, a drug Tetra is developing as a potential treatment for neurological disorders such as Alzheimer’s disease (AD) and one that aims to both improve memory and slow disease progression. The NIH Blueprint Neurotherapeutics…
A recent review discussed how genes implicated in aging and Alzheimer’s disease exhibit epigenetic changes, indicating the same changes might exert a pathogenic role in dementia. The study, titled “Epigenetics of Aging and Alzheimer’s Disease: Implications for Pharmacogenomics and Drug Response,” was published in the International Journal of Molecular…
Drinking alcohol in moderation every day — defined as two-to-three units per day — may be associated with a significantly lower mortality among people with early stage Alzheimer’s disease (AD), according to a Danish study recently published in the BMJ Open journal and titled “Alcohol consumption and mortality in patients with mild…
High levels of stress can increase the likelihood of elderly people developing mild cognitive impairment — usually a precursor to Alzheimer’s disease. These results are reported in a study titled “Influence of Perceived Stress on Incident Amnestic Mild Cognitive Impairment: Results From the Einstein Aging Study,” published in the…
Men undergoing androgen deprivation therapy (ADT) for prostate cancer could be almost twice as likely to be diagnosed with Alzheimer’s disease (AD) than those not treated with ADT. The findings, in a study published in the Journal of Clinical Oncology, also show that the risks of developing Alzheimer’s might continue…
Results from a recent study published in the Scandinavian Journal of Public Health show that mean healthcare costs of patients with Alzheimer’s disease (AD) are significantly higher than of a similar age without AD, starting to increase one year before diagnosis and peaking six months after the disease…
Results from a recent study presented at the 8th International Conference on Clinical Trials for Alzheimer’s Disease (CTAD) revealed that aerobic exercise improves brain function and reduces neurodegeneration markers in older adults at risk for Alzheimer’s disease (AD). Study results also indicate that aerobic exercise may be a potential disease-modifying intervention…
In a recent study published in the journal JAMDA, a team of researchers from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London determined that online games that challenge memory and cognitive skills could beneficially improve daily life for older people. The team demonstrated specifically…
Findings from a recent study published in the Journal of Alzheimer’s Disease revealed that chemical alterations in brain cells triggered by disruptions in the body’s day-night cycle may be an underlying cause of the memory and learning loss observed in Alzheimer’s disease (AD). The study, conducted by University of California researchers,…
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