A protein that’s involved in calcium transport within nerve cells was linked to sporadic Alzheimer’s disease by scientists working in Spain. This protein, called STIM1, may hold promise as a biomarker of this common and non-familial form of Alzheimer’s. Importantly, common treatments for hypertension that are based on dihydropyridine — and…
Using a technique called genome-wide mapping, researchers were able to identify specific variations in RNA splicing from brain tissue taken from 450 people who were part of clinical studies into aging. This work — which identified hundreds of altered splicing events, which affect protein production — in Alzheimer’s, and may…
Scientists have discovered why some people who have brain markers of Alzheimer’s disease, such as protein plaques and tangles, do not develop dementia. The reason may lie in the structure of synapses — the points of contact between nerve cells that allow them to communicate. Findings were published in the study,…
The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS), the largest genetic database on Alzheimer’s disease, will soon begin to make large sets of DNA sequences available to researchers. Analysis of these large sets of genomic data may help identify genetic risks and protective factors…
The study of axonal transport, the system responsible for transporting vital molecules and signals from one nerve cell to another, may lead scientists to the origin of Alzheimer’s disease, according to researchers at the University at Buffalo, New York. Malfunctions in this transport system create “traffic jams,” and…
Get regular updates to your inbox.