Researchers from the UNSW School of Biotechnology and Biomolecular Sciences and School of Medical Sciences and the Neuroscience Research Australia have uncovered a new molecular mechanism responsible for the loss of synapses, a key event in the early pathogenesis of Alzheimer’s disease. The research paper, entitled “Aβ-dependent reduction of…
University of California researchers recently showed that the targeting of a neurotransmitter involved in stress responses significantly reduced cellular and tissue damage while preventing the onset of cognitive impairment in a transgenic mice model of Alzheimer’s disease. The study, entitled “Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology…
A research team attempting to identify new biomarkers of Alzheimer’s disease has found that young subjects at high genetic risk of Alzheimer’s development — while moving through a virtual maze — showed lower brain cell activity involved in spatial navigation than a control group, revealing differences in the brain decades before possible disease onset. The…
Researchers at the Thomas Jefferson University have found a new protein involved in synaptic pathways with important implications in Alzheimer’s disease. The research paper, entitled “Anchoring and synaptic stability of PSD-95 is driven by ephrin-B3,” was published in Nature Neuroscience. Synapses are electrical or chemical signals between…
Researchers from the Rowan University School of Osteopathic Medicine have reported the ongoing development of a blood test for early Alzheimer’s’ disease diagnostic. The preliminary data was presented during the recent Osteopathic Medical Conference & Exposition (OMED 15) in Orlando, Florida. The innovative blood test relies on the detection of autoantibodies as blood biomarkers of…
A new study reports the finding of fungal cells and hyphae in tissue from different regions of the central nervous system (CNS) in Alzheimer’s disease (AD) patients. The research article, entitled “Different Brain Regions are Infected with Fungi in Alzheimer’s Disease”, was published in Scientific Reports. AD…
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