Author Archives: Margarida Azevedo, MSc

In Early Alzheimer’s Disease, Impaired Blood-Brain Barrier May Lead to Cognitive Decline, Researchers Say

Researchers at the Maastricht University Medical Center have investigated how the permeability of the blood-brain barrier (BBB) is involved in early forms of Alzheimer disease. The findings suggest that a faulty BBB may be involved in the initial pathologic process that eventually results in neurodegeneration and dementia in these patients. Researchers…

Chronically Active Innate Immune System Seen as Likely Cause of Dementia in Alzheimer’s Patients

Chronic activation of the innate immune system is the main cause of a range of symptoms common to different neurodegenerative diseases, namely dementia, which is often associated with Alzheimer’s disease, researchers at the University of Adelaide reported. Their study, titled “The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism…

Navigation Problems in New Places May Hint at Preclinical Alzheimer’s Disease

Washington University researchers suggest that difficulties in establishing cognitive maps of new surroundings might indicate the onset of Alzheimer’s disease long before a clinical diagnosis. The findings suggest that navigational tasks can be a powerful new tool for early detection of Alzheimer’s disease-related changes. The research paper, “Spatial Navigation in…

Aduhelm Approved