Margarida Azevedo, MSc,  —

Margarida graduated with a BS in Health Sciences from the University of Lisbon and a MSc in Biotechnology from Instituto Superior Técnico (IST-UL). She worked as a molecular biologist research associate at a Cambridge UK-based biotech company that discovers and develops therapeutic, fully human monoclonal antibodies.

Articles by Margarida Azevedo

Top Scientists Starting Consortium to Improve Trials of Potential Alzheimer’s Therapies

Three leading Alzheimer’s researchers are forming a consortium to improve clinical trials in the field — an effort boosted by a $70 million grant from the National Institutes of Health. Goals of the Alzheimer’s Clinical Trials Consortium include sharing information and resources to make drug development more efficient and finding better…

In Early Alzheimer’s Disease, Impaired Blood-Brain Barrier May Lead to Cognitive Decline, Researchers Say

Researchers at the Maastricht University Medical Center have investigated how the permeability of the blood-brain barrier (BBB) is involved in early forms of Alzheimer disease. The findings suggest that a faulty BBB may be involved in the initial pathologic process that eventually results in neurodegeneration and dementia in these patients. Researchers…

$10M Fund for Brain Degeneration Research Created by Lauder, Newhouse Foundations

The Alzheimer’s Drug Discovery Foundation (ADDF) and the Association for Frontotemporal Degeneration (AFTD) have announced a partnership to find a drug to cure or slow the progression of neurodegenerative diseases caused by the degeneration of neurons. The Lauder Foundation and the Samuel I. Newhouse Foundation will each invest $5 million for the development…

Chronically Active Innate Immune System Seen as Likely Cause of Dementia in Alzheimer’s Patients

Chronic activation of the innate immune system is the main cause of a range of symptoms common to different neurodegenerative diseases, namely dementia, which is often associated with Alzheimer’s disease, researchers at the University of Adelaide reported. Their study, titled “The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism…

Specific Enzyme, a Protein Kinase, Found to Correlate with Neuronal Damage in Alzheimer’s

Increased activity of mutant forms of a specific enzyme, protein kinase Cα (PKCα), correlates with damage to neurons caused by the amyloid-beta protein in late-onset Alzheimer’s disease, researchers from the University of California, San Diego, School of Medicine and Harvard Medical School reported. The findings also suggest that drugs inhibiting the…

Navigation Problems in New Places May Hint at Preclinical Alzheimer’s Disease

Washington University researchers suggest that difficulties in establishing cognitive maps of new surroundings might indicate the onset of Alzheimer’s disease long before a clinical diagnosis. The findings suggest that navigational tasks can be a powerful new tool for early detection of Alzheimer’s disease-related changes. The research paper, “Spatial Navigation in…