A group of patients with inherited forms of Alzheimer’s disease was found to have extremely high brain-aluminum levels, leading researchers to suggest there might be a link between genetic vulnerability to the condition and a higher susceptibility to accumulate aluminum in the brain. “Aluminium in brain tissue in familial…
As the disappointment over the failure of solanezumab begins to wane, George Vradenburg, co-founder and chairman of UsAgainstAlzheimer’s, seeks to address the efforts needed to continue research and clinical development for Alzheimer’s disease. Despite the inability of Eli Lilly to bring the goods to the table, Vradenburg applauded Lilly’s…
Honor is collaborating with the Alzheimer’s Association to educate its Care Pros on how to better care for people living with Alzheimer’s disease. Start-up company Honor offers tech-powered home care for older adults. The new agreement follows similar collaborations, such as the National Parkinson Foundation and the American Cancer Society.
Genervon Biopharmaceuticals recently shared a previously confidential list of 84 genes linked to Alzheimer’s disease which are modulated by their investigational treatment GM6. The move to make the list public was based on a wish to encourage more neurological scientists to investigate broader, multi-target approaches to treat diseases…
A change in the shape of a protein, rather than its size, is the driving force in small protein aggregates morphing into the insoluble structures present in the brains of Alzheimer’s patients — a process known as nucleation, according to a study. Because the aggregates, known as amyloid-beta oligomers, are…
Neither high cholesterol intake nor daily egg consumption increases the risk of dementia or Alzheimer’s disease (AD), according to a study of Finnish men. In fact, moderate egg intake may improve cognitive performance, researchers said. The study also showed no link between men with the APOE4 gene and the development…
Researchers at Rush and Harvard universities are preparing a pioneering clinical trial to evaluate the impact of diet in preventing cognitive decline and Alzheimer’s disease (AD) in older people. The randomized Phase 3 trial (NCT02817074), titled “MIND Diet Intervention and Cognitive Decline,” will test whether a healthy diet…
A Mediterranean diet may protect against the loss of brain volume associated with aging, researchers report. But eating more fish and less meat was not seen to be related to such beneficial changes, which suggests that other components of the Mediterranean diet — or the sum of all its parts — may be…
Researchers have used a novel approach to identify changes in painting patterns that could signal an artist is developing Alzheimer’s disease or another neurodegenerative condition before symptoms show. The team used fractal analysis to look at seven painters’ “artistic fingerprints” over time. Because the changes may occur before cognitive impairment shows…
Researchers have discovered that amyloid-beta — the protein that builds in the brain of Alzheimer’s disease patients — has different structures when it accumulates around blood vessels and neurons. Although the researchers could not conclude how these differences impact the disease, they believe that amyloid buildup around blood vessels differs in…
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